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Objetivo: Evaluar la asociación entre la violencia íntima de pareja emocional, física y sexual con el auto reporte de secreción y úlcera genital en mujeres participantes de una encuesta poblacional. Métodos: Se realizó un análisis de la Encuesta Demográfica y de Salud Familiar del Perú, 2021. Los criterios de inclusión fueron tener 15 a 49 años, ser casadas o convivientes, y estar seleccionadas y entrevistadas para el módulo de violencia doméstica. Se estimó la prevalencia de auto reporte de secreción y úlcera genital. La asociación con la violencia íntima de pareja fue realizada mediante regresión logística binaria con la estimación de la razón de momios, considerando el diseño muestral complejo. Resultados: La prevalencia del reporte de úlcera o secreción genital fue 10,0%. La razón de momios para reportar secreción o úlcera genital entre las mujeres que sufrieron violencia física leve comparado con las no expuestas fue 2,25 (IC95%: 1,72 a 2,94), el riesgo incrementó a 3,42 (IC95%; 2,39 a 4,90) entre las mujeres que sufrieron violencia física severa. La razón de momios generada por la exposición a violencia sexual para reportar secreción o úlcera fue mayor (OR: 3,84, IC95%: 2,47 a 5,96). Conclusiones: Las mujeres expuestas a cada uno de los tres tipos de violencia íntima de pareja tuvieron mayor chance de reportar secreción o úlcera genital en los últimos 12 meses. El riesgo se incrementa cuando coexisten la forma física y sexual.
Objective: To assess the association between emotional, physical, and sexual intimate partner violence with self-reported discharge and genital ulcer in women from participants in a population-based survey. Methods: An analysis of the Demographic and Family Health Survey of Peru, 2021 was performed. Inclusion criteria were 15-49 years of age, married or cohabiting, and selected and interviewed for the domestic violence module. The prevalence of self-reported discharge and genital ulcer was estimated. The association with intimate partner violence was performed by binary logistic regression with odds ratio estimation, considering the complex sample design. Results: The prevalence of reporting genital ulcer or discharge was 10.0%. The odds ratio for reporting genital discharge or ulcer among women who suffered mild physical violence compared with those not exposed was 2.25 (95%CI: 1.72-2.94), the risk increased to 3.42 (95%CI: 2.39-4.90) among women who suffered severe physical violence. The odds ratio generated by exposure to sexual violence for reporting discharge or ulcer was higher (odds ratio: 3.84, 95% CI: 2.47-5.96). Conclusions: Women exposed to each of the three types of intimate partner violence had a higher chance of reporting genital discharge or ulcer in the last 12 months. The risk increases when physical and sexual violence coexist.
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Introduction: In developing countries, reproductive tract infection among women commonly goes undiagnosed and their sequel causes various complications. Objectives: To find out the prevalence of RTI/STI through a syndromic case approach and its correlates among women of reproductive age group. Material and Methods: A community-based cross-sectional study was carried out among 500 eligible married women residing in urban slums of Agra by using WHO Syndromic case approch for diagnosis of RTIs/STIs. Results: The overall prevalence of RTI/STD was found to be 32.80% where vaginal discharge (22.60%) and lower abdominal pain (8.20%) were the most common syndromes. On multivariate analysis, religion, caste, type of absorbent used during menses, and history of IUD use were found to be significantly significant. Conclusion: The result of this study highlights the high prevalence and potential risk factors that contribute to the occurrence of RTI. It also emphasizes the need of training and education session of the participants to identify the early symptoms of RTI.
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Background : Reproductive Tract Infection (RTI) due to poor hygiene caused by faecal Bacteria or viruses which goes into the vaginal canal during and after defecation is not only damaging to the reproductive organ, but also causes indirect or direct impact on Socio-economic status of the patient and their family as well. Objective : This study highlights the importance of faecal hygiene in preventing damage to the reproductive tract and curbing the impact on social and economic problems in patients and their families. Materials and Methods : This study was conducted at GICE Nursing Home, Kalyani, Nadia, WB, between April 2016 and March, 2022. During this period, 11,872 cases were reported at GICE Nursing Home of which 10,000 cases were selected. Discussion : It was interesting to observe that those who wipe from back to front or vice versa are more likely suffering from Vaginitis (85%), Cervicitis (92%), Endometritis (55%), PID (60%), UTI (70%) and Tubal Block (17%) as compared to those who used Hand shower (10%) or Tissue Paper (9%). This is an indication that proper faecal hygiene can prevent damage to the reproductive system. Further analysis revealed that the inability to pay for medical expenses created a Socio-economic crisis among family members. Conclusion : It is concluded from this study that maintenance of proper faecal hygiene by women in Rural, Urban and Industrial areas, can not only help with prolonged illnesses but also prevent financial losses. As a result, Guardians, Teachers, Health Care Providers and Local Government should conduct outreach programs to teach the importance of faecal hygiene at home, in Schools, Colleges, Public health institutions and so on, etc
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Objective:To investigate the changes in procalcitonin (PCT) and C-reactive protein (CRP) levels in married women with genital ureaplasma urealyticum infection and analyze the risk factors of genital ureaplasma urealyticum infection.Methods:A total of 116 married women with genital ureaplasma urealyticum infection who received treatment in the First Affiliated Hospital of Wenzhou Medical University from January 2019 to December 2019 were included in the observation group. An additional 50 healthy married women who concurrently received physical examination in the same hospital were included in the control group. Serum levels of PCT and CRP were compared between the two groups. Questionnaire outcomes and the risk factors for genital ureaplasma urealyticum infection were subjected to univariate analysis and logistic regression analysis.Results:Serum levels of PCT and CRP in the observation group were (3.71 ± 0.64) μg/L and (34.26 ± 4.23) mg/L, respectively, which were significantly higher than those in the control group [(0.49 ± 0.16) μg/L, (4.84 ± 0.75) mg/L, t = 35.05, 48.76, both P < 0.001]. In the observation group, the proportions of women who used condom each time, who had no abortion, who had one sexual partner, who had first sexual intercourse at the age of ≥ 20 years, who had sexual intercourse ≤ 3 times/week, who had no history of unclean sexual contact, and who knew knowledge of genital ureaplasma urealyticum infection were 54.55%, 24.24%, 65.15%, 54.55%, 42.42%, 69.70%, 34.85%, respectively, which were significantly lower than those in the control group [80.00%, 48.00%, 88.00%, 76.00%, 66.00%, 94.00%, 60.00%, χ2 = 9.79, 9.33, 8.81, 6.89, 7.89, 11.56, 9.32, P = 0.002, 0.009, 0.003, 0.008, 0.005, 0.001, 0.002). Multivariate analysis showed that abortion frequency, number of sexual partners, age at first sexual intercourse < 20 years, frequency of sexual intercourse and history of unclean sexual contact were independent risk factors for genital ureaplasma urealyticum infection ( OR = 2.12, 3.58, 2.34, 2.84, 4.24). Frequent condom use and knowledge of genital ureaplasma urealyticum infection were protective factors for genital ureaplasma urealyticum infection ( OR = 4.03, 3.03). Conclusion:Abnormal increases in serum PCT and CRP levels in married women can be used as sensitive indicators for early diagnosis of genital ureaplasma urealyticum infection. Frequency of sexual intercourse, number of sexual partners, more times of abortion, premature sexual activity, and history of unclean sexual contact are the risk factors of genital ureaplasma urealyticum infection.
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Objective:To observe the effect of Gongyanping Capsule on genital tract infected by ureaplasma urealyticum and fertility of mice, and to explore its mechanism.Methods:One hundred female ICR mice were divided into normal control group, model control group, azithromycin group, the low and high-dose group of Gongyanping Capsule according to random number table method. Except for the normal control group, the other groups were infected with ureaplasma urealyticum to establish the reproductive tract inflammation model. The azithromycin group was given 40 mg/kg of azithromycin, the low and high-dose groups were given 50 and 100 mg/kg of Gongyanping Capsule respectively, the normal control group and model control group were given equal volume of normal saline, once a day, for 4 consecutive weeks. The fertility status of each group was recorded. HE staining was used to observe the pathological changes of the vaginal tissues of the mice in each group, and the content of monocyte chemoattractant protein 1 (MCP-1), IL-4, IL-12, TNF-α myeloperoxidase (MPO) and GSH-Px of the mice in each group were determined; RT-PCR and Western blot were used to determine the vagina level of mRNA and protein expressions of TLR4 and NF-κB.Results:Compared with the model control group, the birth time and the number of dead mice in the azithromycin group and the low and high dose groups of Gongyanping Capsule decreased ( P<0.05), and the number of born mice increased ( P<0.05). The level of MCP-1, MPO, IL-4, IL-12, TNF-α decreased ( P<0.05), the level of GSH-Px increased ( P<0.05), the expression of TLR4 mRNA (1.25±0.33, 2.97±0.92, 2.32±0.72 vs. 3.69±1.32), NF-κB mRNA (1.48±0.42, 2.91±0.99, 2.13±0.70 vs. 3.83±1.41) decreased ( P<0.05), the expression of TLR4 (0.63±0.13, 1.32 ± 0.34, 1.04 ± 0.33 vs. 1.63 ± 0.41), NF-κB (0.63 ± 0.14, 1.36 ± 0.32, 1.03 ± 0.30 vs. 1.94 ± 0.58) decreased ( P<0.05), and had a certain dose-dependence. Conclusion:Gongyanping Capsule has obvious therapeutic effect on genital tract mice infected by ureaplasma urealyticum, and can significantly improve the fertility of mice; the mechanism may be related to that Gongyanping Capsule could inhibit the vaginal TLR4/NF-κB pathway in mice.
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Objective To investigate the clinical characteristics of preadolescent and adolescent female patients with ovarian mass combined with dysplasia of secondary sexual characteristics. Methods This study retrospectively analyzed 18 cases of ovarian mass combined with dysplasia of secondary sexual characteristics aged 0-19 years admitted to Peking Union Medical College Hospital from January 2012 to November 2019.By analyzing the clinical manifestations,surgical methods,postoperative pathology,therapies and prognosis of the cases,we summarized the diagnosis and treatment ideas. Results Among the 18 cases,7(7/18,38.9%)developed secondary sex signs before puberty,including 5 cases showing precocity(including 2 cases of juvenile granulosa cell tumor,1 case of gonadoblastoma,1 case of ovarian follicular cyst,and 1 case of 46,XY simple gonadal dysplasia combined with dysgerminoma)and 2 cases presenting masculine manifestations(1 case of steroid cell tumor and 1 case of sclerosing stromal tumor).The rest 11(11/18,61.1%)cases showed abnormal development of secondary sexual characteristics during puberty,including 8 cases with masculine manifestations or abnormal menstruation after menarche(7 cases with sex cord stromal cell tumor and 1 case with cystic granulosa cell tumor),2 cases with primary amenorrhea(1 case with androgen insensitivity syndrome combined with testicular sertoli cell tumor and 1 case with endometriosis cyst combined with reproductive tract malformation),and 1 case diagnosed as 46,XX gonadal dysplasia with serous cystadenoma and no secondary sexual development during puberty. Conclusions Sex hormone levels should be actively tested in the case of prepubertal secondary sexual characteristics appearing early,pubertal secondary sexual characteristics being abnormal(underdevelopment),and/or menstrual abnormalities.Imaging examination should be performed to exclude ovarian organic lesions,and chromosome karyotype analysis should be performed if necessary.The diagnosis of ovarian mass in preadolescent and adolescent females with related symptoms should first be alerted to cord stromal cell tumor.It is recommended to rule out the possibility of combined reproductive tract malformation in the adolescent patients with primary amenorrhea.Chromosome examination should be conducted to rule out the possibility of gonadal dysplasia in the adolescent patients with primary amenorrhea and/or no development of secondary sexual characteristics.
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Adolescent , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Young Adult , Hyperplasia/complications , Ovarian Neoplasms/pathology , Retrospective StudiesABSTRACT
RESUMEN Fundamento: la infertilidad es la incapacidad para tener hijos, pero con posibilidad de embarazo que no llega a término. En el mundo existen 187 millones de parejas afectadas. Objetivo: caracterizar las mujeres atendidas en la consulta municipal de infertilidad. Métodos: se realizó un estudio descriptivo observacional y retrospectivo en Policlínico Docente Emilio Daudin Bueno, de la provincia Guantánamo, durante el periodo enero de 2017 a junio de 2020. El universo estuvo constituido por las 128 mujeres infértiles de 19-39 años atendidas en consulta. Fueron evaluadas variables cualitativas y cuantitativas. La información de cada variable estudiada se obtuvo de las historias clínicas de las pacientes atendidas en consulta. Resultados: predominaron las féminas de 25-29 años con infertilidad secundaria; las infecciones genitales como factor causal predominante, seguido de los antecedentes obstétricos desfavorables y en la mayoría de las pacientes el peso saludable como evaluación nutricional. Se pudo percibir que del total de las pacientes, en algunas existió algún grado de aumento del peso corporal. Conclusiones: la consulta de infertilidad cumple el objetivo de lograr la concepción de las féminas según las causas que impiden la misma, la actuación de cada profesional de la salud al incorporar los conocimientos necesarios a emplear en su adecuado seguimiento, permitirá concretarlo desde la Atención Primaria de Salud.
ABSTRACT Background: infertility is the inability to have children, but with the possibility of pregnancy, which does not reach term. There are one hundred and eighty-seven million affected couples in the world. Objective: to characterize women treated in the municipal consultation of infertility. Methods: an observational and retrospective descriptive study was carried out in Emilio Daudinot Bueno Docent Polyclinic, Guantánamo, during the period January 2017 to June 2020. The universe was made up of 128 infertile women who met the inclusion criteria: 19-39 years old, seen in infertility consultation and fulfill the concept of infertility. Qualitative and quantitative variables were evaluated. The primary data was obtained from the medical records of the patients seen. Results: females aged 25-29 years with secondary infertility predominated; genital infections as the predominant cause factor, followed by unfavorable obstetric history and, in most patients, healthy weight as a nutritional assessment. It was possible to perceive that of the total number of patients, in some there was some degree of increase in body weight. Conclusions: the infertility consultation fulfills the objective of achieving the conception of women by attenuating the causes that prevent it, the performance of each health professional by incorporating the necessary knowledge to be used in its adequate follow-up, will allow specifying it from Primary Care of health.
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La infección por Chlamydia trachomatis es la infección de transmisión sexual bacteriana más frecuente en el mundo. En este artículo se revisa la prevalencia reportada en Chile, cuadro clínico, diagnóstico, tratamiento, prevención y complicaciones a largo plazo en mujeres.
Chlamydia trachomatis infection is known to be the most common sexually transmitted bacterial infection world-wide. This article reviews the prevalence reported in the Chilean population, as well as the clinical manifestations, diagnosis, treatment, prevention and complications in women
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Humans , Female , Chlamydia Infections/diagnosis , Chlamydia Infections/therapy , Chlamydia trachomatis , Chlamydia Infections/complications , Chlamydia Infections/physiopathology , Chlamydia Infections/prevention & control , Risk FactorsABSTRACT
OBJECTIVE@#To investigate the value of clinical application of simultaneous amplification and testing of RNA (SAT-RNA) for detecting Chlamydia trachomatis (CT) and Ureaplasma urealyticum (UU) by comparing with the polymerase chain reaction testing of DNA (PCR-DNA) method.@*METHODS@#Specimens from both urethra swab and the first avoid urine which should be at least one hour after the previous urination were collected from 163 men who were scheduled for in vitro fertilization and embryo transfer (IVF-ET) treatment due to female factors at Center for Reproductive Medicine, Shengjing Hospital of China Medical University during the period of April 2016 to April 2017. Among the 163 men, 109 simultaneously provided semen that was collected after 3-7 days of sexual abstinence for the testing. Urine and semen specimens were detected for CT and UU with SAT-RNA, while urethra swab specimens were detected for CT and UU with standard PCR-DNA. Detection results of the SAT-RNA were compared with those of the PCR-DNA method.@*RESULTS@#The positive rate of UU in the urethra swab detected with PCR-DNA and that of UU in the urine with SAT-RNA were 47.24% and 47.85%, respectively, and the coincidence rate was 93.25%. In addition, the positive and negative coincidence rates were 93.51% and 93.02%, respectively, and the concordance between the two methods was very good (Kappa=0.865). On the other hand, the positive rate of CT in the swab specimen tested with PCR-DNA was 3.07% and that of CT in urine with SAT-RNA was 4.29%, and the coincidence rate was 97.55%. Moreover, the positive and negative coincidence rates were 80.00% and 98.10%, respectively, and the concordance between the two methods was good (Kappa=0.654). Regarding SAT-RNA detection of UU in the urine and semen specimen of the 109 patients, the positive rates of UU in the urine and semen specimens were 50.46% and 44.95%, respectively; and the coincidence rate between the two specimens was 88.99%. In addition, the positive coincidence rate and the negative coincidence rate was 93.88% and 85.00%, respectively, and the concordance between the two specimens was good (Kappa=0.780). Similarly, SAT-RNA detection of CT in the urine and semen specimens showed the positive rate was 5.50% and 3.67%, respectively; and the two specimens showed 98.17% coincidence rate. The positive and negative coincidence rates were 100.00% and 98.10%, respectively, and the concordance was also good (Kappa=0.791).@*CONCLUSION@#SAT-RNA detection of CT and UU in the urine specimen showed good concordance with the PCR-DNA detection of CT and UU in the urethra swab specimen. In addition, the concordance was also good between the urine and semen specimens detected with SAT-RNA. These results indicate that, as a less invasive and equally accurate procedure, SAT-RNA may be more suitable for clinical application.
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Female , Humans , Male , Chlamydia Infections/epidemiology , Chlamydia trachomatis/genetics , Infertility, Male , Neisseria gonorrhoeae/genetics , Polymerase Chain Reaction , Ureaplasma urealyticum/geneticsABSTRACT
The emergence of a large number of drug-resistant bacteria has brought severe challenges to clinical anti-infection treatment. Phage therapy is considered to be a very promising method to cope with this dilemma, which has been explored and applied in many disciplines. Its efficacy has also been confirmed in clearing skin and mucous membrane infections, and it has become a hot spot in international research. The use of phage cocktails, phage lysozymes and phage proteins has shown good efficacy in the treatment of drug-resistant Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella, Bacillus proteus, etc. This review summarizes the background, characteristics, development of phage therapy, and its application and prospects in skin and genitourinary tract infections.
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Background: Reproductive tract infection (RTI) is a public health problem, especially in developing country like India. The associated odium with this reproductive morbidity is often a stumbling block in seeking health care. The aim was to study the prevalence of RTI symptoms and its socio-demographic corelates.Methods: A cross-sectional study was undertaken in the rural field practice area of department of community medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India, from July 2018 to September 2018. Total sample size calculated was 410. Random sampling was used to select eligible couple to whom a predesigned, pretested, semi-structured and anonymous interview schedule was administered after taking consent.Results: The prevalence of self-reported reproductive tract infections was found to be 41.2%. The prevalence was more in lower socio-economic classes, and it was statistically significant. Other socio-demographic corelates (age, education, occupation) did not showed any significant association.Conclusions: The reproductive tract infections prevalence is found to be considerably high in the women of reproductive age group. The frequency was higher among multigravida women and those using cloth during menstrual periods. RTIs are usually spurned by women and even the health care providers, so there is a need to give due consideration to this aspect of reproductive health.
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Background: Syphilis is a sexually transmitted disease (STD) caused by the bacterium treponema pallidum, but little is known about its mechanism of action. In pregnancy it leads to adverse outcomes among more than half of the women with active disease, including early fetal loss, stillbirth, prematurity, low birth weight, neonatal and infant death.Methods: It is an observational study in the department of obstetrics and gynecology Mahatma Gandhi Memorial Medical College Maharaja Yashwant Rao Hospital, Indore between January 2014 to December 2015 total 20870. In Include written informed consent, All the patients attending STI/RTI clinic with clinical diagnosis of STD. In Exclusion criteria include patients not give informed consent. Case definition: All VDRL + TPHA positive patients.Results: Out of 20870 females on which VDRL was performed 77 (0.036%) were found to be positive. The seroprevalence at study hospital thus came out to be 0.036%. These were further confirmed by TPHA and 73 (94.8%) out of 77 samples were positive. A total agreement was seen between TPHA and VDRL with a titer of 1 in 8 and above. Among total 20870 screened females, 77% (16101) were ANC patients of which 26 cases out of 77 that is 33.76% females were syphilis positive.Conclusions: Low prevalence of syphilis in pregnant women and adult general population is very encouraging. participation of people and public health approach to promote awareness of syphilis among physicians and populations at risk in India are very urgently needed to avoid the adverse consequences which could result from undiagnosed or improper treatment.
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RESUMEN Fundamento: la infección genital causada por el virus del papiloma humano es una infección de transmisión sexual común, que afecta a millones de personas de todo el mundo. Objetivo: determinar el comportamiento del papiloma virus humano de localización genital en adolescentes y jóvenes femeninas menores de 25 años. Métodos: se realizó un estudio descriptivo transversal en menores de 25 años atendidas en la consulta de patología de cuello del Policlínico de Nuevitas en el período comprendido desde enero a diciembre de 2016; con un universo de 93 pacientes con diagnóstico confirmado de papiloma virus humano en la citología orgánica. Resultados: el mayor número de las pacientes con papiloma virus humano presentaron lesiones intraepiteliales, con predominio de alto grado. Más de la mitad de las lesiones correspondieron al grupo de jóvenes entre 20 y 24 años. Se observó relación de la presencia del virus con varios factores de riesgos, casi la totalidad tuvieron su primeras relaciones sexuales precozmente. Alrededor de la tercera parte tuvieron relaciones sexuales múltiples, prevalecieron entre tres y cinco parejas sexuales, fue relevante la ectopia cervical, como antecedentes ginecológicos se observó la leucorrea como síntoma más frecuente. Conclusiones: existe una estrecha relación entre adolescentes con riesgos y presencia del papiloma virus humano, la presencia de este virus es un factor predisponente para que se presenten lesiones intraepiteliales cervicales.
ABSTRACT Background: genital infection caused by human papillomavirus is a common sexually transmitted infection, which affects millions of people around the world. Objective: to determine the behavior of human papillomavirus of genital location in adolescents and young women under 25 years. Methods: a cross-sectional descriptive study was carried out in girls under 25 years of age attended in the neck pathology clinic of the Nuevitas Polyclinic in the period from January to December 2016; with a universe of 93 patients that with confirmed diagnosis of human papillomavirus in organic cytology. Results: the greatest number of patients with human papillomavirus presented intraepithelial lesions, with a high degree of predominance. More than half of the injuries corresponded to the group of young people between 20 and 24 years old. Relationship of the presence of the virus with several risk factors was observed, almost all had their first sexual intercourse early. Around the third part of them had multiple sexual relations, three to five sexual partners prevailed, cervical ectopia was relevant, as gynecological history, leukorrhea was observed as the most frequent symptom. Conclusions: there is a close relationship between adolescents with risks and presence of human papillomavirus, the presence of this virus is a predisposing factor for cervical intraepithelial lesions.
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Introduction: Reproductive tract infections (RTIs) are a universal public health problem among young women in developingcountries and occupy the second position in public health problems. RTIs lead to 17% of economic losses in these countries.According to the WHO estimates in 2008, globally, 499 million new cases of RTIs occurred annually among women in thereproductive age group. In India, one among four women in the reproductive age group has any one type of RTIs and the annualincidence of RTI estimated is about 5%. Consequently, the prevalence rate of RTIs in various states of India is 19%–71%. Thereare about 40% of women estimated to have RTIs/sexually transmitted infections (RTI/STI) at any given point of time, but only1% complete the full course of treatment of both partners. The present study was conducted to know about the knowledge,attitude, and practices about the RTI/STIs among the antenatal mothers attending outpatient departments in Goa MedicalCollege as part of needs assessment for formulating educational and preventive strategies.Materials and Methods: This cross-sectional descriptive study was conducted at Goa Medical College, a Tertiary Care Hospital atBambolim-Goa, from December 2018 until February 2019. Institutional Ethics Committee (IEC) approval was taken from the IEC ofthe Goa Medical College. Data were collected by interviewing mothers using a semi-structured questionnaire. Additive scores weredeveloped for awareness, knowledge, and perceptions in specific areas of transmission, prevention, and treatment of RTI/STI. Thescores were characterized as poor, average, and good. Data were entered in EpiData Manager and analyzed using SPSS 22 version.Categorical variables were expressed in percentages and proportions and quantitative variables in mean ± SD. The associationbetween dependent and independent variables was assessed using bivariate analysis. P < 0.05 was taken as statistically significant.Aims and Objectives: The aims of the study were (1) to study the level of awareness regarding RTIs/STIs among antenatalmothers, (2) to study their knowledge regarding symptoms and modes of transmission of RTI/STI, (3) to study awarenessregarding preventive strategies for transmission of RTI/STIs, and (4) to study their attitudes and perceptions toward STIs.Results: The mean age of the study participants was 27.5 years. The majority of antenatal mothers, i.e., 64% were aware of RTI/STIsin our study. There was poor awareness in 46% of study subjects and good awareness in 28% of study subjects. On bivariate analysis,awareness was significantly related to education level (P = 0.000), occupation (P = 0.002), socioeconomic status (P = 0.000), andlocation (P = 0.000). About 59% antenatal mothers knew whitish discharge per vaginum as the most common symptom of STI/RTI.The other symptoms identified were lower abdominal pain by 56%, itching in perineal region by 40%, weakness by 50%, and lossof weight by 22%. The mode of spread of RTI/STIs was identified as a sexual route by 56% and blood transfusion by 35% and 31%and 30% were of the opinion that unhygienic conditions and unsafe deliveries were the modes of spread of RTI/STIs, respectively.About 50% antenatal mothers were aware that safe sexual practices can prevent STI/RTIs, 36% felt that the use of condoms helpsin preventing STI/RTIs, 22% opined that good personal hygiene is the mode of preventing RTI/STIs, and 31% were ignorant aboutits prevention. Thus, 67% subjects had poor knowledge, 24%average knowledge and good knowledge was present in only9% study subjects. On bivariate analysis, knowledge wassignificantly related to age (P = 0.04), education (P = 0.03),occupation (P = 0.002), and location (P = 0.015). Socioeconomicstatus shows significant linear by linear relation trends. About74% study, subjects felt that RTI should be treated to avoidcomplications, while 23% did not want to express themselves.Similarly, 20% subjects refused to talk about STIs. Half of the study participants (48%) had a poor score with respect to perception about STI/RTI. Only 19% had good scores which were significantlyrelated to education (P = 0.012), occupation (P = 0.001), and location (P = 0.000).Conclusion: The study findings show that although there is 64% awareness of STI/RTI, there is a lack of requisite knowledgewith respect to RTIs. The attitude, knowledge, and perception are significantly related to education, occupation, and location.Therefore, the knowledge has to be spread in society through educational programs so as to increase awareness of this problem,thereby curbing the spread of RTI/ STIs and their complications.
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Objective To determine the association of asymptomatic sexually transmitted infections (STIs) with high-risk human papillomavirus (hrHPV) in cervical squamous intraepithelial lesions and neoplasms. Methods From July 2017 to July 2018, 320 hrHPV-positive and 160 hrHPV-negative women in The First Affiliated Hospital of Xi'an Jiaotong University were divided into normal+low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL)+ invasive cervical cancer (ICC) subgroups, respectively, based on their pathological cervical lesion grades. Cervical brush specimens including Ureaplasma urealyticum (UU) and its serotypes, Mycoplasma hominis (MH), Mycoplasma genitalium (MG), Chlamydia trachomatis (CT), and hrHPV were amplified and hybridized using PCR kits (Hybribio Biochemistry Co., Ltd.). The differences between groups were examined by the chi-squared test, continuity correction and Logistic regression. Results The overall infection (at least one of the non-hrHPV pathogens was positive) rates of the two groups were 62.5% and 59.4%, which were not significantly different. The prevalence of UU was the highest. The prevalence of UU serotype 14 (Uup14) and MH was associated with hrHPV (P=0.003, P=0.005, respectively), but not with certain hrHPV genotypes or with single or multiple genotypes. Compared with cases of normal+LSIL, cases of HSIL+ICC had significantly different Uup14 infection rates (OR: 12.579, 95% CI: 3.638-43.497, P<0.001) in the positive group. In hrHPV-negative cases, there were obvious differences in Uuu and Uup1 infections based on different cervical lesion types (OR: 11.646, 95% CI: 1.493-90.850, P=0.019; OR: 7.474, 95% CI: 1.140-49.015, P=0.036). Conclusion Asymptomatic STIs in female lower reproductive tract are widespread. Uup14 may increase the risk of HSIL+ICC when hrHPV is positive. Uuu and Uup1 cause an increased risk of HSIL+ICC without hrHPV.
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Introduction: Ureaplasma urealyticum and Mycoplasma hominis are frequently found at many women's and men's urogenital tract, and have been associated with non-gonococcal urethritis, cervicitis, infertility, chorioaminionitis and adverse pregnancy outcomes. Some studies show high prevalence of human papillomavirus (HPV) in patients with non-gonococcal urethritis, while also presenting high frequency of Ureaplasma urealyticum infection in women with cervicalcytology abnormalities and men with genital warts. Objectives: To evaluate the prevalence of Ureaplasma urealyticum, Mycoplasma hominis and HPV coinfection in people attending a sexually transmitted infections (STI)/HIV reference centre and to identify the risk factors associated. Methods: A cross-sectional study with patients aged >18 years, carried out for Ureaplasma urealyticum and Mycoplasma hominis from July 1st to December 31, 2015, in a STI/HIV reference centre from the State of Bahia, Brazil. Sociodemographic and clinical data were obtained from secondary data from patients' charts and laboratory findings, and analyzed using SPSS 20.0. Pearson's χ2 test or Fisher's exact test was used to evaluate categorical variables. HPV clinical diagnosis was considered positive as the presence of genital warts. Results: In this study, 849 patients were included 196 men and 653 women. Of the sample, 51.4% was diagnosed with at least one of the two bacteria. The prevalence of Mycoplasma hominis infection was higher in coinfection (16.7%) than in isolated infection (2.2%). The prevalence of Ureaplasma urealyticum isolated infection was 32.4%. A strong association was found between the presence of genital warts and Ureaplasma urealyticum infection, with an estimated risk of 1.230 (p=0.014). Conclusion: Our findings suggest the need for further investigation for Ureaplasma urealyticum infection in patients presenting genital warts on physical examination. In addition, in this context, greater attention should be given to women and pregnant women.
Introdução: Ureaplasma urealyticum e Mycoplasma hominis são frequentemente encontrados no trato urogenital de homens e mulheres, e têm sido associados à ocorrência de uretrites não gonocócicas, cervicites, infertilidade, corioamnionite e outras patologias obstétricas. Alguns estudos mostraram alta prevalência de papilomavírus humano (HPV) em pacientes com uretrites não gonocócicas, bem como alta frequência de infecção por Ureaplasma urealyticum em mulheres com anormalidades na citologia cervical e homens apresentando verruga genital. Objetivos: Avaliar a prevalência da coinfecção por Ureaplasma urealyticum, Mycoplasma hominis e HPV em pessoas atendidas em um centro de referência de DST/HIV e identificar os fatores de risco associados. Métodos: Estudo transversal com pacientes maiores de 18 anos, testados para Ureaplasma urealyticum e Mycoplasma hominis entre 1º de julho e 31 de dezembro de 2015, em um centro de referência de DST/HIV da Bahia, Brasil. Os dados clínicos e sociodemográficos foram obtidos por coleta de dados secundários a partir dos prontuários e achados laboratoriais dos pacientes e analisados usando SPSS 20.0. O teste de χ2 Pearson ou teste exato de Fisher foram usados para avaliar as variáveis categóricas. O diagnóstico clínico do HPV foi considerado positivo quando houve presença de verruga genital. Resultados: Foram incluídos neste estudo, 849 pacientes, sendo 196 homens e 653 mulheres. Da amostra, 51,4% foi diagnosticada com infecção por pelo menos uma das duas bactérias. A prevalência de infecção por Mycoplasma hominis foi maior na coinfecção (16,7%) do que isoladamente (2,2%). A prevalência da infecção isolada por Ureaplasma urealyticum foi de 32,4%. Houve forte associação entre a presença de verruga genital e infecção por Ureaplasma urealyticum, com estimativa de risco de 1,230 (p=0,014). Conclusão: Nossos achados sugerem a necessidade de investigação adicional para a infecção por Ureaplasma urealyticum nos pacientes apresentando verruga genital ao exame físico. Além disso, nesse contexto, maior atenção deve ser dada a mulheres e gestantes.
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Humans , Papillomaviridae , Ureaplasma urealyticum , Mycoplasma hominis , Urethritis , Warts , MycoplasmaABSTRACT
Background: Lack of awareness and poor hygiene practices during menstruation can lead to various gynecological problems in the reproductive life of girls. Menstruation is still considered as unclean in the Indian society. Objectives: The objective of the study is to assess the hygiene practices among adolescent girls with special reference to menstrual hygiene in urban area of Barpeta and to assess the restrictions practiced by them during menstruation. Materials and Methods: It was a community-based cross-sectional study involving 200 adolescent girls of Barpeta conducted from August 2018 to January 2019. The data were collected using predesigned and pretested pro forma. Results: The study revealed that 92% of the respondents knew about menstruation before menarche. As high as 92% of the respondents believed that menstruation occurs due to natural or hormonal cause, whereas 1.5% considered it as a disease process. 81.5% girls used commercially available sanitary pads and 78.5% girls cleaned external genitalia with soap and water. All the participants avoid attending religious occasion, followed by kitchen work (57.5%), marriage party (31.5%), and 30.5% of them were sleeping separately. 46% of the respondent avoid sour food during menstruation. Conclusion: Although awareness regarding menstrual hygiene is quite satisfactory in majority of the respondents, yet false perceptions, ignorance, and unsafe practices are still prevailing in the community. Behavior change communication to bring about safe and hygienic practices during menstruation through different stakeholders will help in solving menstruation-related problems among the adolescent girls.
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Background: Ujjain is holy city of Lord Mahankal. It is an ancient city on the eastern bank of the Kshipra River. There were total 2508 students studying in 11th and 12th standards in various higher secondary schools of Ujjain city. Reproductive health is a crucial part of general health and a central feature of human development. It is a reflection of health during childhood and crucial during adolescence and adulthood, sets the stage for health beyond the reproductive years. Adolescence is a complex period of myriad of physiological as well psychological changes. This is a time for them to prepare for making responsibilities, a time of exploration and widening horizons and a time to ensure healthy all-around development. Adolescents lack knowledge regarding reproductive health problems. The present study is conducted to assess the knowledge, attitude and practices regarding selected aspects of reproductive health with special reference to knowledge of Reproductive tract infections (RTI) among adolescent school students.Methods: This was a cross sectional study carried out among randomly selected school students of Ujjain city.Results: It was observed that 86% of the students had adequate knowledge in the area of pregnancy and care during pregnancy. The mean score percentage of reproductive tract infection was found to be 56.92%. 90.50% students agreed that Menstruation is normal phenomenon.Conclusions: There is need of imparting sex education in schools across the country with the help of specially trained teachers and peer educators.
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Background: Genital infections, a major cause of illness among women in reproductive age group, affect their quality of life and social living. Early diagnosis and treatment of STI/RTI is also an important aspect in prevention of HIV transmission. As there are only a handful of studies in Kerala and none in Kannur assessing the prevalence, associated factors of genital infections and health seeking behaviour among women in reproductive age group, this study stands important.Methods: A community based descriptive study was conducted in Kulappuram area of Cheruthazham Panchayat which is the field practice area of Department of Community Medicine, Government Medical College, Kannur, Pariyaram from June, 2017 – July, 2018. A total of 404 women in reproductive a group were studied. A semi-structured, pre-tested questionnaire was used to collect relevant information. Data was analyzed using SPSS-version 19 software.Results: The mean age of the study population was 32.20±10.741years. 52.7% of the study population had genital infection, with 40.6% having symptoms of Reproductive Tract Infections (RTI) and 12.1%, symptoms of Urinary tract Infections (UTI). The presence of these was significantly associated with menstrual disorders, cloth as menstrual pad users, marriage, sexual activity and absence of infertility. Only 39.0% of the women with infections had sought treatment.Conclusions: Although there was high prevalence of genital infections among the study population, treatment seeking behaviour was very low. There is a need for sustained motivation and support to promote women to seek timely medical care than to suffer silently.
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Background: The word adolescent is derived from the Latin word “adolescere”, which means to grow into maturity. The adolescent girls get debarred due to various social misconceptions, lack of privacy, illiteracy of parents, especially mother, low socioeconomic conditions, and lack of proper health awareness and education about this sensitive issue which ultimately results this age group into vulnerability to reproductive tract infections, which can be reduced by improving the knowledge about the menstrual hygiene. Methods: A cross sectional study was conducted among school going adolescent girls during the month of November 2018. Data was collected using a questionnaire which includes socio-demographic variables and menstrual hygiene practices. Sample size of the study was 69 students. The assessment of knowledge was done as good knowledge (score: >5/10) poor knowledge (score <5/10). The of data and the. All the data collected was entered and analysed with MS excel software 2007. Results: 28.1% girls were aware of menstruation prior to attainment of menarche.. Major source of information about menstruation is mother (53.6%). More than 80% of adolescent girls are using sanitary pads as an absorbent. Lack of disposal facility and lack of water supply are reasons for school absenteeism. Conclusions: In this study the knowledge of menstruation hygiene among the study population is significantly associated with mother’s education and occupation.